期刊文献+

结直肠癌化学治疗临床研究进展 被引量:3

Recent progress in chemotherapy of colorectal cancer
下载PDF
导出
摘要 氟尿嘧啶联合醛氢叶酸钙(FL方案)已成为结直肠癌的标准治疗方案,且以FL静脉持续滴注方案为优;口服氟尿嘧啶类药物在生存率上至少与已确立的FL方案相当,而毒副反应方面则更优越;奥沙利铂(L-OHP)与FL联合使用在高危结直肠癌治疗中显示出比标准FL方案有生存上的优势,3年无瘤生存率更高。分子靶向药物和有效抗肿瘤细胞毒药物的联合序贯应用进一步延长转移性结直肠癌患者的生存期,但最佳给药顺序仍有争论。
出处 《国外医学(肿瘤学分册)》 CAS 2005年第6期457-461,共5页 Foreign Medical Sciences (Cancer Section)
  • 相关文献

参考文献29

  • 1Dickson J, Cunningham D. Towards new standards in the adjuvant treatment of colorectal cancer. 15^th ICACT Proceeding Book(Paris),2004,32-35.
  • 2Andre T, Boni C, Mounedji-Boudiaf L, et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med,2004,350(23) : 2343-2351.
  • 3Mayer RJ. Two steps forward in the treatment of colorectal cancer. N Engl J Med, 2004,350(23) : 2406-2408.
  • 4Saltz LB, Niedzwiecki D, Hollis D, et al. Irinotecan plus fluorouracil/leucovorin (IFL) versus fluorouracil/leucovorin alone (FL) in stage Ⅲ colon cancer (Intergroup trial CALGB C89803 ). Proc Am Soc Clin Oncol, 2004,23:246.
  • 5Cassidy J, Scheithaner W, McKendrick J. Capecitabine (X) vs bolus 5-FU/leucovorin (LV) as adjuvant therapy for colon cancer (the X-ACT study): efficacy results of a phase Ⅲ study. Proc Am Soc Clin Oncol, 2004,23(Suppl) : 14.
  • 6Wolmark N, Wieland S, Lembersky B, et al. A phase Ⅲ trial comparing oral UFT to FULV in stage Ⅱ and Ⅲ carcinoma of the colon : results of NSABP Protocol C-06. Proc Am Soc Clin Oncol, 2004,23(Suppl) : 14.
  • 7Figueredo A, Charette ML, Maroun J, et al. Adjuvant Therapy for Stage Ⅱ Colon Cancer: A Systematic Review From the Cancer Care Ontario Program in Evidence-Based Care's Gastrointestinal Cancer Disease Site Group. J Clin Oncol. 2004.22(16) : 3395-3407.
  • 8Gray RG, Barnwell J, Hills R, et al. QUASAR: a randomized study of adjuvant chemotherapy (CT) vs. observation including 3238 colorectal cancer patients. Proc Am Soc Clin Oncol, 2004,23:246.
  • 9Benson AB, Schrag D, Somerfield MR, et al. American Society of Clinical Oncology Recommendations on Adjuvant Chemotherapy for Stage Ⅱ Colon Cancer. J Clin Oncol, 2004,22(16) : 3408-3419.
  • 10Goldberg RM, Sargent DJ, Morton RF, et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol,2004,22( 1 ) : 23-30.

同被引文献28

引证文献3

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部