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Interaction between Ternary Rare Earth Complexes of Cinnamic Acid and Phenanthroline with DNA by Spectroscopy 被引量:3

Interaction between Ternary Rare Earth Complexes of Cinnamic Acid and Phenanthroline with DNA by Spectroscopy
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摘要 The interaction of ternary complexes [RE(phen)(cin)_3(H_2O)](RE= Nd (III),Ce(III),Eu(III))with calf thymus DNA was investigated by electronic absorption spectroscopy, ethidium bromide(EB)-DNA quenching fluorescent spectra and resonance light scattering. All experimental results indicate that the three complexes bind to DNA by the electrostatic mode and the intercalative mode. It is predicted that these complexes show high anticancer activity or other biologic activity. The interaction of ternary complexes [RE(phen)(cin)_3(H_2O)](RE= Nd (III),Ce(III),Eu(III))with calf thymus DNA was investigated by electronic absorption spectroscopy, ethidium bromide(EB)-DNA quenching fluorescent spectra and resonance light scattering. All experimental results indicate that the three complexes bind to DNA by the electrostatic mode and the intercalative mode. It is predicted that these complexes show high anticancer activity or other biologic activity.
出处 《Journal of Rare Earths》 SCIE EI CAS CSCD 2005年第2期162-166,共5页 稀土学报(英文版)
基金 ProjectsupportedbytheNationalNaturalScienceFoundationofChina(20171019)
关键词 inorganic chemistry electrostatic and intercalative mode EB-DNA quenching fluorescent spectroscopy absorption spectroscopy resonance light scattering rare earth complexes inorganic chemistry electrostatic and intercalative mode EB-DNA quenching fluorescent spectroscopy absorption spectroscopy resonance light scattering rare earth complexes
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