摘要
采用高效液相色谱外标法，以甲醇溶液（取甲醇４００ｍｌ，乙腈２００ｍｌ及冰醋酸０．６ｍｌ混匀）－０．２％无水硫酸钠的醋酸铵溶液（１→１００）（７：３）为流动相，检测波长２３０ｎｍ测定枸橼酸芬太尼注射液的含量，浓度在０．４～１．６μｇ范围内呈良好线性关系，相关系数ｒ＝０．９９９０，回收率为９９．９％，ＲＳＤ为１．４８％。
new Nethod for the determination of fentanyl citrate injection is reported,7volum of nethanol soluton(methanol 400ml,acetonitrile 200ml and glaial acetic acid 0.6ml)and 3 volum of 0.2%anhydrous sodium sulphate in ammonium ac-etate solution(1-100)was used as mobile phase detection wavelength was 230nm,recovery was 99.9%(RSD=1.5%)the method was more convenient practical selective compared to other methods reported
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1994年第8期343-344,共2页
Chinese Journal of Hospital Pharmacy
