摘要
药物临床研究的计算机模拟是近年来刚兴起的一门交叉学科。该技术的成功运用,可大大降低新药开发费用、缩短研发时间,有广泛的应用前景。本文从药动学和药效学的角度对其发展历史、内容、方法和应用作一综述。
Clinical trial simulation is a newly evolved interdiscipline with pr o mising future. Its appropriate and successful implementation helps to reduce the cost and time of the new drug development process. In this paper, the history, application and general methodology of the technique was reviewed from the pharm acokinetics and pharmacology point of view.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2005年第6期491-496,共6页
Chinese Journal of New Drugs and Clinical Remedies
关键词
药学
研究
计算机模拟
药动学/药效
学模型
pharmacy
research
computer simulation
pharmacokinetics/ pharmaco dynamics model
