摘要
目的比较以胎儿脐带和巩膜为材料行后巩膜加固术后碱性成纤维细胞生长因子(basicfibroblastgrowthfactor,bFGF)的表达,选择一种更为理想的手术材料。方法对24只家兔左右眼分别以人巩膜和胎儿脐带为材料行后巩膜加固术,于术后2,4,12和24周取材进行免疫组织化学染色检查。结果两种材料后巩膜加固术后炎症细胞、成纤细胞均有bFGF表达,但脐带加固材料组bFGF表达明显强于巩膜加固材料组,且持续时间长。结论胎儿脐带是一种更为理想的后巩膜加固术材料。
[Objective]To study the expression of basic fibroblast growth factor (bFGF) after scleral reinforcement by means of umbilical cord and sclera grafting in order to select an ideal sclera reinforcement material. 24 rabbits underwent scleral reinforcement in right eye with umbilical cord and left eye with human sclera, respectively. The expression of bFGF was studied by immunohistochemistry at 2, 4, 12, 24 weeks after operation. The expression of bFGF in inflammatory cells and fibroblast was significantly more and persisted longer in umbilical cord group than in human sclera group. [Conclusion] Umbilical cord is more ideal material for scleral reinforcement operation.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2005年第8期1192-1193,1197,共3页
China Journal of Modern Medicine
