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双黄连气雾剂与注射剂的药效学及临床应用研究 被引量:22

Studies on Pharmacodynamics and Clinical TherapeuticEffccts of Aerosol and Injection of Shuanghuanglian
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摘要 药效学实验表明:双黄连两种剂型均能增强人外周血NK细胞活性,具有促进淋巴细胞生成α-干扰素的能力,同时具有广谱抑菌、抑病毒作用。以注射剂生物利用度为100%,气雾剂绝对生物利用度为96.88%(黄芩甙)和96.69%(绿原酸),临账观察表明:气雾剂与注射剂的显效率分别为84%和83%,总有效率分别为92%和93%。 he results show that both aerosol and injection of shuanghuanglian can increase. the activity of NK cells in pe-ripheral blood of the human body as well as the ability of lymphocyte to produce α-interferon. Their broad-spectrumantiseptic and virus-inhibiting actions have also been confirmed.The absolute bioavailability of aerosol was 96.88%(baicalin) and 90. 69% (chlorogeniacid).The significant response rate of aerosol and injection was 84% and 83% re-spectively. The total response rate was 92% and 93% respectively.
出处 《中国中药杂志》 CAS CSCD 北大核心 1994年第11期689-692,共4页 China Journal of Chinese Materia Medica
关键词 双黄连 气雾剂 注射剂 临床应用 药理 e Shuanghuanglian: aerosol injection : pharmacedynamics clinical therapeutic effects
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