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吡格列酮对2型糖尿病患者糖和脂质代谢的影响 被引量：4

THE AFFECT OF PIOGLITAZONE ON CARBOHYDRATE AND LIPID METABOLISM OF PATIENTS WITH DIABETES Ⅱ
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摘要 目的观察盐酸吡格列酮对2型糖尿病患者血糖、血脂代谢的影响。方法75例接受磺脲类和/或双胍类降血糖治疗的2型糖尿病患者进行12w随机、双盲、安慰剂平行对照的临床试验。结果吡格列酮能明显增加磺脲或胍类降血糖药物对2型糖尿病的治疗效果,治疗8w后A组FBG、PBG分别下降了1.04mmol/L、3.15mmol/L,12w后,A组FBG、PBG、HhbA1C分别下降了1.67mmol/L、3.04mmol/L和20.5%,治疗12w后A组TG下降明显,HDL-Ch与治疗前及B组比较增高较明显。结论盐酸吡格列酮可改善2型糖尿病患者的血糖及血脂代谢,有助于防治糖尿病血管并发症,是较为理想的抗糖尿病新药。
作者 刘卓
机构地区 娄底市中心医院
出处 《现代医院》 2005年第6期13-15,共3页 Modern Hospitals
关键词 吡格列酮 2型糖尿病 糖代谢 脂质代谢 药物治疗
分类号 R587.1 [医药卫生—内分泌] R977.15 [医药卫生—药品]
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参考文献11

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二级参考文献6

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现代医院
2005年 第6期

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