摘要
作者测定了59例成人严重脑外伤(GCS≤8分)入院时(≤6小时)血糖含量,结合临床病情及预后进行对比研究,结果表明:脑外伤组血糖水平显著高于正常值(P<0.05);入院时血糖水平与GCS显著相关(P<0.001);GCS3~4分、5~6分、7~8分三组入院时的血糖含量分别平均为12.32±3.15、9.08±2.98、6.24±1.07(mmol/L)。入院时血糖水平与病人的预后亦显著相关(P<0.001);伤后1月内恢复良好、差、死亡三组病人入院时血糖含量分别平均为6.11±1.01、8.39±1.79、12.36±3.34(mmol/L)。入院时血糖含量≥10mmol/L者,死亡率明显增高(P<0.001)。结合文献,讨论了严重脑外伤急性期高血糖反应的发生机理,对预后的影响及处理等问题。
The admission serum glucose level was measured in 59 adult patients with severe head injury (GCS≤8) within 6 hours after injury. The results showed that (1) The admission serum glucose level was significantly higher in the patients than normal value ( P< 0.05);(2) The lower the GCS score was, the higher the serum glucose level was ( P< 0.001). The patients with GCS of 3~4, 5~6,7~8 had mean admission serum glucose levels of 12.32±3.15, 9.08±2.98, 6.24±1.07 (mmol/L) respectively; (3) The admission serum glucose level was correlated with GCS of these patient ( P< 0.001), the patients in the 3 groups of the dead, poor recovery and good recovery in the first month after injury had mean admission serum glucose levels of 12.36±3.34, 8.39±1.79, 6.11±1.01 (mmol/L) respectively; (4) The patients with admission serum glucose level≥10 mmol/L had significantly higher death rate during the first month postinjury ( P< 0.001). These data suggests that admission hyperglycemia is a frequent component of the stress response to severe head injury, a significant indicator of severity, and a significant predictor of outcome for severe head injury.
出处
《中华创伤杂志》
CAS
CSCD
北大核心
1994年第1期2-4,共3页
Chinese Journal of Trauma
关键词
脑外伤
血糖
急性病
Acute head injury Serum glucose