摘要
利用桥接物修复１．０ｃｍ以上神经缺损，效果不理想。本实验采用自体静脉桥接家兔４．０ｃｍ长胫神经缺损，术后２个月未发生神经再生现象。而利用自体静脉内种植雪旺氏细胞匀浆，桥接家兔４．０ｃｍ长胫神经缺损，术后电生理、组织学、透射电镜等项检测指标都能观察到神经再生现象。雪旺氏细胞匀浆在静脉桥接物的这一作用，增加了非神经移植物修复神经缺损的长度。
he purpose of this experimental study is to pursue the method of schwann’s
cell plantation to improve the result of bridginglonger nerve defect with autogenous vein
graft.Rabits were used and devided into 3 groups (group A.group B, group C)Thelength of nerve
defects was 4cm. In group A, We bridged a 4.0cm long peroneal nerve defect in the rabbits only
with an autoge-nous vein, and no nerve regeneration was found two months after the operation.
Group B was bridged by 4.0cm nerve defect withautogenous vein of schwann cells
plantation,Group C bridged by 4.0cm nerve defect with autogenous nerve. The results
showedthat the bioelectric activity could pass through the graft planted by schwann cells and
the axon regeneration was better than the graft without schwann cells in histology and
ultrastructure. It is concluded that Schwann cells could survive in the graft and act asa bridge to
guide and improve the axon regeneration.
出处
《中华创伤杂志》
CAS
CSCD
北大核心
1994年第4期152-154,共3页
Chinese Journal of Trauma
