摘要
应用ＥＬＩＳＡ检测３１５例产妇血清及其新生儿脐血清抗丙型肝炎病毒（抗－ＨＣＶ）。结果表明抗－ＨＣＶ阳性产妇的新生儿部分亦呈阳性，肝功能异常产妇抗－ＨＣＶ阳性率及其新生儿抗－ＨＣＶ阳性率呈明显高值，且显示与年龄增长呈正相关，提示产妇尤其是肝功能异常产妇，除应检测乙型肝炎病毒（ＨＢＶ）五项指标外，还应常规检测抗－ＨＣＶ，有条件者还应采用逆转录聚合酶链反应检测脐血ＨＣＶ－ＲＮＡ，以确诊有无母儿垂直传播。
Detection of serum antibody of hepatitis C virusfanti-HCV) with ELISA kits was performed in 315parturients and their newborns. The results indicatedthat some of the infants, born of mothers infected withHCV were also anti-HCV positive, and a high posi-tive rate of abnormal maternal hepato-function har-bored a markedly positive rate of anti-HCV both inmother and newborn and bore a positive correlation tothe maternal age. These suggest that besides the fiveroutine tests, anti-HCV should better be determined,especially in mothers with abnormal hepato-function.If possible, in such cases HCV-RNA should be exa-mined by using revert nested polymerase chain reac-tion technique to determine whether a verticalmother-infant transmission exists.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1994年第6期328-329,共2页
Chinese Journal of Obstetrics and Gynecology
关键词
丙型肝炎病毒
免疫球蛋白
免疫技术
Immunoenzyme techniqueHepatitis C virus Immunoglobulins
