摘要
用免疫组织化学和计算机辅助图像分析的方法检测良性前列腺增生(BPH)组织中平滑肌成分的含量。结果表明,良性前列腺增生组织中平滑肌占间质成分的面积百分比明显高于正常前列腺组织。间质中平滑肌成分的含量与良性前列腺增生的临床症状评分、最大尿流率、平均尿流率密切相关,但与年龄和前列腺的大小无关。
Immunohistochemistry and computer-assisted quantitative image analysis were used to quantify the area density of smooth muscle of the prostatic stroma in 22 cases of benign prostate hyperplasia (BPH)and 20cases of normal prostate specimens.The area density of smooth muscle in BPH stroma(34. 01 ± 7. 08) was stastically higher than that in normal prostate(26.06± 8.54),( P< 0.01 ).A statically significant correlation was observed between the area density of smooth muscle and the peak urinary flow rate,the average urinary flow rate and the international prostate symptom score.No correlation was observed between the area density of smooth muscle and the volum of prostate neither the age of patients.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
1994年第3期184-186,共3页
Chinese Journal of Urology
基金
国家自然科学基金
关键词
前列腺增生
免疫组织化学
计算机
Immunohistochemistry Benign prostatic hyperplasia