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耳蜗性聋的畸变产物耳声发射测试 被引量:3

Distortion product otoacoustic emission test of cochlear deafness
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摘要 目的 :通过畸变产物耳声发射 (DPOAE)测试耳蜗性聋的敏感性、特异性和符合率来评估其测试效能。方法 :测试听力正常人 86耳和耳蜗性聋 98耳的DPOAE ,其 1~ 6kHz各个频率的幅值与对应频率的电测听纯音听阈相比较 ,用所得到患耳蜗性聋敏感性和特异性值作受试者作业特征曲线 ,并计算其面积 ,其面积值并不因为DPOAE用于区别听力正常与否的取值标准不同而发生变化 ,用所得到的面积值来判断DPOAE的测试效能。结果 :1~ 6kHz从低到高各个频率对应的受试者特征曲线面积分别为 0 .6 77,0 .777,0 .818,0 .890 ,0 .873。结论 :DPOAE可以作为测试耳蜗性聋的一种频率特异性的客观方法。 Objective: To evaluate the performance of the distortion product otoacoustic emissions (DPOAE) test of cochlear deafness by measuring the sensitivity, specificity and predictive efficiency of the test.Method:With DPOAE examination data obtained from normal hearing (86 ears) and cochlear deafness (98 ears), the evaluation was performed by comparing the outcomes of the DPOAE level test at each of several frequencies (1~6 kHz) with those of the pure tone audiogram. The sensitivity and specificity were combined to form receiver operating characteristics(ROC) curves. The area under an ROC curve was calculated to represent a useful overall measure of a test's performance independent of the particular choice of a criterion value of a test variable separating the normal from abnormal.Result:The area under an ROC curve at 1, 2, 3, 4, 6 kHz frequencies was 0.677 , 0.777 , 0.818 , 0.890 , 0.873 , respectively.Conclusion:The DPOAE can form a useful frequency specific objective test of cochlear deafness.
出处 《临床耳鼻咽喉科杂志》 CAS CSCD 北大核心 2003年第10期588-590,共3页 Journal of Clinical Otorhinolaryngology
关键词 畸变产物耳声发射 ROS曲线 听力丧失 Distortion product otoacoustic emissions Receiver operating characteristics Hearing loss
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参考文献7

  • 1宇传华.诊断试验的评价[A].见:余松林.医学统计学[M].北京:人民卫生出版社,2002.164-178.
  • 2刘爱国,崔永华,葛新,王春芳.不同声强度刺激对畸变产物耳声发射的影响[J].复旦学报(医学版),2003,30(3):243-245. 被引量:1
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二级参考文献4

  • 1Whitehead ML, Lonsbury-Martin BL, Martin GK. Evidence for two discrete sources of 2f1-f2 distortion-product otoacoustic emission in rabbit. I . Differential dependence on stimulus parameters. J Acoust Soc Am, 1992,91:1587
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