摘要
７０例膀胱移行细胞癌β－ＨＣＧ免疫组织化学测定和３４例膀胱癌患者血清、尿β－ＨＣＧ放射免疫测定发现，随着肿瘤分级的上升，组织β－ＨＣＧ表达阳性率也提高；随着肿瘤分期进展，组织及血清、尿β－ＨＣＧ阳性率明显增高。研究表明，组织及血清、尿β－ＨＣＧ的测定可作为判断膀胱癌预后的指标，阳性者近期内肿瘤转移死亡率明显高于阴性者。
Beta human chorionic gonadotrophin (β- HCG) immunohistochemical study of tumor tissue in 70 and serum and urine β-HCG radioimmunoassay in 34 patients with carcinoma of the bladder were carried out. The results revealed that β-HCG expression was more frequent in high grade and invasive tumor, the positive rate of elevated level of β-HCG in serum and urine being increased as tumor stage progressed. Our results suggest that β-HCG might serve as a prognostic marker of bladder tumor, as the patients with β-HCG positive expression in tumor tissue and elevated level in serum and/or urine had higher metastatic mortality than those with negative expression or normal level.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
1994年第1期30-32,共3页
Chinese Journal of Urology
关键词
膀胱肿瘤
癌
预后
Β-HCG
Bladder neoplasms Carcinoma Prognosis Gonadotropins, chorionic
