摘要
用病毒学及免疫学方法研究了玫瑰糠疹与柯萨奇Ｂ组病毒感染的关系。结果表明，急性期患者血清抗柯萨奇Ｂ组病毒特异性ＩｇＭ的阳性率明显高于健康对照组，血清循环免疫复合物的含量急性期明显高于恢复期，中和试验和病毒分离都证明患者体内有柯萨奇Ｂ组病毒感染。这些结果提示，玫瑰糠疹的发病与柯萨奇Ｂ组病毒感染有直接关系，而造成免疫病理损伤的原因是柯萨奇Ｂ组病毒与其相应抗体形成的循环免疫复合物。
Relationship between pityriasis rosea and Cox- sackie B virus (CBV) infection was studied by virolog- ic and immunologic methods. The results indicated that the positive rate of serum anti-CBV(B group)IgM an- tibody of the patients in acute stage was significantly higher than that of heahhy control. The level of serum circulating immune complex in acute stage was signifi- cantly higher than that in convalescent stage. Neutral- ization tests and virus isolation also proved that the patients was infected by CBV. These results suggest that the pathogenesis of pityriasis rosea may be related to CBV in fection, and CIC, which was composed of CBV and its antibody, led to the immunopathological damage of the patients.
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
1994年第3期144-145,共2页
Chinese Journal of Dermatology
基金
吉林省卫生厅资助课题
关键词
玫瑰糠疹
柯萨奇病毒B
Pityriasis rosea Coxsackie B viruses
