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同种异体冻干骨加钛笼在颈前路减压融合术中的应用 被引量:4

Combined titanium mesh cages with freeze-dried bone allograft for anterior cervical decompression and fusion
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摘要 目的观察同种异体冻干骨加钛笼结合动力型颈前路钢板在颈椎前路减压融合术后的融合情况.方法对122例颈椎病病人行颈前路减压、钛笼加同种异体冻干骨植骨结合动力型颈前路钢板内固定术.于术前、术后6个月进行日本骨科疗效(JOA)评分,观察神经功能恢复情况;术后6个月、1年观察钛笼植骨融合率及早期沉降率.结果术后对116例随访12~22个月,平均17个月.症状均明显缓解,脊髓功能明显改善;JOA评分由术前的8.6分改善至14.1分.根据Zdeblick标准,术后6、12个月钛笼植骨融合率分别达到92.0%和95.6%,而沉降出现率分别为16.0%和18.6%.无钢板和螺钉松动或断裂现象存在.结论同种异体冻干骨加钛笼作为颈椎前路减压融合手术中的支撑性植骨材料,融合率满意,沉降率低. Objective To observe the fusion rate of titanium mesh (Ti-mesh) with allogeneic freeze-dried bone (FDB) after anterior cervical decompression (ACD) and fusion (ACDF). Methods 122 cervical spondylosis patients were treated by implantation of FDB with Ti-mesh and internal fixation with dynamic plate after ACD. Clinical status of preoperation and 6 months postoperation were scored respectively by Japanese Orthopaedic Association (JOA) system to evaluate the recovery of nerve function. Fusion rate and early subsidence were observed at 6 and 12 months postoperation respectively. Results 116 patients were followed-up for 12 to 22 months with an average of 17 months. In 6 months postoperative follow-up, JOA score increased from preoperative 8.6 score (ranged from 6 to 12) to postoperative 14.1 (ranged from 12 to 17). According to Zdeblick standard, fusion rate of Ti-mesh with FDB and subsidence rate of the mesh were 92.0% and 16% respectively 6 months postoperation, which were 95.6 % and 18.6 % respectively 12 months postoperation. No looseness or breaking of plate and screw were observed. Conclusion Ti-mesh combined with FDB as an implant for ACDF can achieve high fusion rate and low subsidence rate.
出处 《中国微侵袭神经外科杂志》 CAS 2005年第6期249-250,共2页 Chinese Journal of Minimally Invasive Neurosurgery
关键词 脊柱骨赘病 减压术 外科 移植 同种 内固定器 骨代用品 spinal osteophytosis decompression, surgial transplantation, homologus internal fixators bone substitutes
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参考文献8

  • 1Zdeblick TA, Phillips FM. Interbody cage devices [J]. Spine,2003; 28(15 Suppl): 2-7.
  • 2Simion M, Fontana F. Autogenous and xenogeneic bone grafts for the bone regeneration. A literature review [J].Minerva Stomatol, 2004; 53(5): 191-206.
  • 3Profeta G, de Falco R, Ianniciello G, et al. Preliminary experience with anterior cervical microdiscectomy and interbody titanium cage fusion (Novus CT-Ti) in patients with cervical disc disease [J]. Surg Neurol, 2000; 53(5): 417-426.
  • 4Kubler N, Reuther J, Kirchner T, et al. Osteoinductive, morphologic, and biomechanical properties of autolyzed, antigen-extracted, allogeneic human bone [J]. J Oral Maxillofac Surg, 1993; 51(12): 1346-1357
  • 5Reynolds MA, Aichelmann-Reidy ME, Branch-Mays GL, et al. The efficacy of bone replacement grafts in the treatment of periodontal osseous defects. A systematic review [J]. Ann Periodontol, 2003; 8(1): 227-265.
  • 6Wang JC, McDonough PW, Endow K, et al. The effect of cervical plating on single-level anterior cervical discectomy and fusion [J]. J Spinal Disord, 1999; 12(6): 476-471.
  • 7Hakalo J, Wronski J. Subsidence and its effects on the anterior plate stabilization in the course of cervical interbody spondylodesis. Part Ⅱ. Clinical evaluation. Study design [J].Neurol Neurochir Pol, 2003; 37(5): 1063-1072.
  • 8Herzmann K, Grass R, Barthel S, et al. Allogenic transplanta tion of femoral condyle after traumatic injury [J]. Unfallchirurg,2002; 105(1): 71-74.

同被引文献36

  • 1熊卉,张伟,邓益辉.脱钙冻干异体骨移植对骨缺损的修复作用[J].中华实验外科杂志,2006,23(12):1547-1548. 被引量:8
  • 2唐欣,杨述华,李宝兴,孙世荃.辐照冻干骨板引导羊椎板再生的实验研究[J].中国生物医学工程学报,2007,26(1):138-143. 被引量:2
  • 3中华人民共和国科学技术部.关于善待实验动物的指导性意见.2006.09-30
  • 4Banwart JC,Asher MA,Hassanein RS.Iliac-crest bone graft donor site morbidity:a statistical evaluation.[J]Spine 1995;20:1055-60.
  • 5Silber JS,Anderson DG,Dafiner SD,et al.Donor site morbidity after anterior iliac crest bone harvest for single-level anterior discectomy and fusion[J]Spine 2003;28:134-9.
  • 6Epstein NE Complication avoidance in 116 dynamic-plated singlelevel anterior corpectomy and fusion[J]Journal of Spinal Disorders and Technioues,2005,20(5):347-351.
  • 7Van den Bent MJ,Oosting J,Wouda EJ,van Acker EH,Ansink BJ,Braakman R.Anterior cervical discectomy with or without fusion with acrylate:a randomized trial[J]Spine 1996;21:834-9.
  • 8Gercek E,Arlet V,Delisle J,Marchesi D.Subsidence of stand-al one cervical cages in anterior interbody fusion:warningEur[J]Spine J 2003;12:513-6.
  • 9Vavruch L,Hedlund R,Javid D,Leszniewski W,Shalabi A.A pros pective randomized comparison between the Cloward procedure and a carbon fiber cage in the cervical spine:a clinical and radiologicstudy[J]Spine 2002;27:1694-701.
  • 10Kabir SM,Alabi J,Rezajooi K,et al.Anterior cervical corpeetomy:review and comparison of results using titanium mesh cages and carbon fibre reinforced polymer cages [J].Br J Neurosurg, 2010,24 (5) : 542-546.

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