期刊文献+

小儿“不能切除”的肝母细胞瘤的治疗 被引量:6

Preoperative Chemotherapy for Unresectable Hepatoblas- toma in Children
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摘要 5例"不能切除"的肝母细胞瘤应用以顺铂(CDDP)为主的强效化疗后,肿瘤缩小,成功地施行了二期手术和延期手术,生存5~30个月,提示化疗有效,但不同组织类型其疗效有差异。 Five cases of unresectable hepatoblastoma were trea- ted by intensive preoperative chemotherapy using Cis- platin and Adriamycin,or combined with other agents. In all cases,the tumor reduced in size markedly allowing a successful resection.All the 5 children were living and well.The chemotherapeutic effects,however,depend up- on the histological type of the tumor and its sensitiveness to the drug.
出处 《中华小儿外科杂志》 CSCD 1994年第2期73-75,126,共3页 Chinese Journal of Pediatric Surgery
关键词 肝肿瘤 肝母细胞瘤 外科手术 儿童 Preoperative chemotherapy Unresectable hepatoblastoma
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  • 1杨体泉.小儿恶性实体瘤的综合治疗[J].临床小儿外科杂志,2008,7(1):54-56. 被引量:2
  • 2高解春,金百祥.Ⅲ、Ⅳ期神经母细胞瘤的外科处理:延期和二次手术[J].中华小儿外科杂志,1995,16(2):70-72. 被引量:10
  • 3郑传胜,冯敢生,周汝明,梁波.中药白芨的新用途——栓塞肝动脉治疗肝癌[J].中华肿瘤杂志,1996,18(4):305-307. 被引量:52
  • 4Perilongo G,Shafford E,Maibach R, et al. Risk-adapted treatment for childhood hepatoblastoma, final report of the second study of the International Society of Pacdiatric Oncologu-SIO- PEL2. Eur J Cancer, 2004,40(3) :411-421.
  • 5Meyers RL, Rowland JR, Krailo M, et al. Predictive power of pretreatment prognostic factors in children with hepatoblastoma: a report from the children's oncology group. Pediatr Blood Cancer, 2009, 53(6):1016-1022.
  • 6Roebuck DJ, Aronson D, Clapuyt P, et al. 2005 PRETEXT: a revised staging system for primary malignant tumors of child- hood developed by the SIOPEL group. Pediatr Radiol, 2007, 37(2) : 123-132.
  • 7Von Schweinlitz D. Management of liver tumors in childhood.Semin Pediatr Surg, 2006,15 ( 1 ) .. 17-24.
  • 8Cushing B, Giller R, Cullen JW, et al. Randomized comparison of combination chemotherapy with etoposide, bleomycin, and either high-dose or standard-dose cisplatin in children and adolescents with high-risk maliganant germ cell tumors: a pediatric intergroup study-Pediatric Oncology Group 9049 and Childrerfs Cancer Group 8882. J Clin Oncol, 2004, 22 (13): 2691-2770.
  • 9Malogolowkin MH, Katzenstein HM, Krailo M, et al. Redefining the role of doxorubincin for the treatment of children with hepatoblastoma. J Clin 0ncol,2008,26(14) ..2379-2383.
  • 10Malogolowkin MH, Katzenstein H, Krailo MD, et al. Intensified platinum therapy is an ineffective strategu for improving outcome in pediatric patients with advanced hepatoblastoma. J Clin Oncol, 2006,24 (18) : 2879-2884.

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