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HLA-II类基因与妊娠期糖尿病相关性的研究 被引量:9

Development in study on correlation between HLA class II gene and gestational diabetes mellitus
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摘要 有关HLAII类基因的研究已经涉及到遗传学、免疫学、临床医学。其中HLAII与自身免疫性疾病的相关性是非常重要且引人注目的问题,特别是HLAII类基因与糖尿病相关性研究已取得了一定的结论,HLAII类基因与病理性妊娠的相关研究也有所进展。妊娠期糖尿病的病因及发病机理目前尚不清楚。妊娠期糖尿病为糖尿病的一独立特殊型,它与HLAII类基因相关性的研究已开始起步,不同的HLAII类基因可能控制妊娠期糖尿病的抑制性和易感性。 The study on HLA class II gene involves in genetics, immunology and medicine. The correlation between HLA class II gene and autoimmune diseases is very significant and attractive. Especially, the study on correlation between HLA class II gene and diabetes mellitus has drew some definite conclusions and the study on correlation between HLA class II gene and abnormal pregnancies also has achieved some progresses. So far, the cause and pathogenesis of gestational diabetes mellitus are unclear. Gestational diabetes mellitus is an independent type of diabetes mellitus. The study on mechanism of correlation between gestational diabetes mellitus and HLA class II gene has already started. Some different HLA class II genes may control limitation and susceptibility to gestational diabetes mellitus.
出处 《国外医学(妇幼保健分册)》 2005年第3期150-152,共3页 Foreign Medical Sciences (Section of Maternal and Child Health)
基金 云南省教育厅科研基金资助项目(0593)
关键词 妊娠期糖尿病 HLA—Ⅱ类基因 相关性 gestational diabetes mellitus HLA class II gene correlation
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