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青少年健康人群白喉抗体水平调查分析 被引量:2

An Investigation on the Level of Antibodies against Diphtheria in Teen-age People
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摘要 目的 了解青少年人群抗白喉抗体水平,为预防控制白喉提供依据。方法 采用随机抽样方法抽取调查点和被测人群,用间接血凝试验(IHA)检测抗白喉毒素抗体,结果分析采用χ2 检验和F检验。结果 青少年健康人群白喉抗体阳性率为80 .32 % (15 1/188) ,平均抗体滴度(GMT)为1∶12 .2 2 36 ,抗毒素平均含量(ATC)为0 .0 5 9IU/ml。抗体水平比较分析,年龄组中最高者是9~11岁组(96 .6 7% ) ,最低者是12~14岁组(48.78% ) ;城关(95 .4 5 % )高于农村(72 .13% ) ;男女性别间无差异。结论 岳阳市健康青少年人群的抗白喉抗体水平较高,能够有效防止白喉流行。 Objective The target of this analysis was to investigate the level of antibodies against diphtheria in teen-age people, for providing the foundation of diphtheria control and prevention. Methods The investigation site and the samples from teen-age people were selected with random sampling. By means of indirect hemagglutination assay (IHA) the antibodies against diphtheria toxoid were examined. The results were analyzed with statistics methods, including χ 2 test and F test. Results Of 188 sera from 151 (80.32%) had a significant antbody titer against diphtheria toxoid, in which the geometric mean titer (GMT) was 1/12.2236. In the positive rates of different groups, the most was in 9-11 age group (96.67%), the lowest was in 12-14 age group (48.78%); it was higher in the town than in the countries; and it was no different between males and female. Conclusion The level of antibodies against diphtheriae in teen-age people in our city was high enough to prevent diphtheria epidemic.
出处 《疾病监测》 CAS 2005年第5期249-250,共2页 Disease Surveillance
关键词 白喉杆菌 抗体水平 青少年 预防 间接血凝试验 白喉 Bacilius diphtheriae Antibody level Teen-age people
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