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低密度脂蛋白及其抗体与动脉粥样硬化的关系 被引量：7

Relation Between Arteriosclerosis and Oxidatively Modified Low-Density Lipoprotein as well as Autoantibodies
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摘要 研究表明氧化型低密度脂蛋白是动脉粥样硬化疾病发生发展的关键因素,多种致病因素可导致其在血清中浓度升高,同时该物质的抗体浓度也会升高。氧化型低密度脂蛋白血清中浓度的升高又能导致血栓类和其他心血管疾病的发生发展,检测其抗体可能预测心血管疾病发生及评价冠心病预后。 More and more basic researches have provided strong evidences that OX-LDL plays an important role in the development of arteriosclerosis disease. Several mechanisms have been identified which can lead to LDL oxidation in vivo. The level of anti-OXLDL is related to the level of OX-LDL in the serum of the atherosclerotic patients. OX-LDL can lead to other thrombotic diseases and cardiovascular diseases. So determination of the level of anti-OX- LDL can forecast the occurrence and evaluate the prognosis of cardiovascular diseases.
作者 陈志华 张皓
机构地区 上海第二医科大学仁济医院血管外科
出处 《上海第二医科大学学报》 CSCD 北大核心 2005年第6期638-642,共5页 Acta Universitatis Medicinalis Secondae Shanghai
关键词 氧化型低密度脂蛋白 动脉粥样硬化疾病 白及 发生发展 心血管疾病 致病因素 抗体浓度 疾病发生 升高 冠心病 血清 oxdatively modified low-density lipoprotein autoantibodies atherosclerosis
分类号 R543.5 [医药卫生—心血管疾病] R282.710.7 [医药卫生—中药学]
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参考文献23

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二级参考文献35

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共引文献19

同被引文献118

引证文献7

二级引证文献43

上海第二医科大学学报
2005年 第6期

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