摘要
原发性食管小细胞未分化癌少见。本文对从国内文献收集的137例加上本院的5例共142例进行分析。发病年龄以50~60岁多见,男女之~为3.79:l,肿瘤长径范围为1.2~15cm,平均5.6cm。病变发生于食管上1/3者10例(7.5%)、中1/386例(64.2%)、下1/338例(28.3%)。髓质型50例(41%)、蕈伞型26例(21.3%)、溃疡型24例(19.7%)、腔内型16例(13.1%)、缩窄型6例(4.9%)。统计国内文献各该组发病率为0.7%~5.1%,本院组为0.1%。本病预后主,在可评价疗效的131例中,中位生存期和1年生存率:全组为7.6个月和29%;单纯手术6.3个月和18.4%;单纯放疗11.8个月和36.6%;放疗加化疗12.3个月和50%;手术加化疗12.2个月和39.3%。单纯化疗和手术加放疗中位生存期分别为5.5个月和5个月,无1年生存者。根据资料,作者认为使用放疗或根治性手术加用化疗可以提高本病的疗效。
caseg of primary small cell undifferentisted carcinoma of the esophagus were analysed.137 were collected from the domestic Literature and 5 are added by the authors. The tumor occurred more frequently in patients 50-60 years old. The male to female sex ratio was 3. 79 1 1'On basis of the present data, the authors believe that the survival rate of the disease may be increased by the combination of radiation ot radical resection and systemic chemotherapy'
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1994年第5期305-307,共3页
Cancer Research on Prevention and Treatment
关键词
食管肿瘤
原发性
小细胞未分化癌
分析
Esophagus
primary small cell undifferentiated carcinoma
Combined treatment