摘要
本文检测了一组再生障碍性贫血患者血浆和细胞诱生的肿瘤坏死因子（ＴＮＦａ）和细胞诱生上清的白细胞介素２（ＩＬ－２）。与正常对照比较，再障病人血浆和细胞诱生上清的ＴＮＦａ活性水平明显增高（Ｐ＜０．０１），ＩＬ－２的诱生水平也明显增高（Ｐ＜０．０５），本研究提示ＴＮＦａ和ＩＬ－２在再障的发病中可能有一定的作用。
n order to clarify the role of interleukin 2(IL-2)and tumor necrosis factor alpha(TNFα)in thepathogenesis of aplastic anemia,IL-2 and TNFα level was determined in patients with aplasticanemia. In comparison with normal subjects,TNFα activity was significantly elevated,(P<0.01)andIL-2 level increased also.(P<0.05) It is suggested that abnormal level of TNFα and IL-2 in patientswith aplastic anemia is probably related to the pathogenesis of aplastic anemia.
出处
《重庆医科大学学报》
CAS
CSCD
1994年第2期121-122,共2页
Journal of Chongqing Medical University
