摘要
以低硒（Ｓｅ）、低维生素Ｅ（ＶＥ）粮饲养大鼠，观察其血液流变学指标变化。结果表明，低Ｓｅ、低ＶＥ粮饲养大鼠的红细胞（ＲＢＣ）变形性、ＧＳＨ－ＰＸ和ＣｕＺｎＳＯＤ活力降低，ＲＢＣ压积、ＲＢＣ聚集性、ＲＢＣ聚集指数、脂质过氧化物增高。结果提示，Ｓｅ可能通过改变红细胞内表膜面Ｓｐｅｃｔｒｉｎ蛋白与ＲＢＣ膜骨架结合状态以及Ｓｅ和ＶＥ抗氧化损伤保护细胞膜结构完整性的作用，影响ＲＢＣ的变形性。
Hemorheological indexes were determined in rats. which were fed grains of deficency.Selenium(Se) and Vitamin E(VE).The results showed that the hematocrit, erythrocyte aggregation and erythrocyte aggregation index, LPO were significantly higher than those of the control, but erythrocyte deformability, GSH-PX and CuZnSOD activity were reduced. The results suggested that the dietary deficency of Se and VE may change condition of combination Spectrin with RBC membrane so that effect on erythrocyte deformability.
出处
《微循环学杂志》
1994年第4期14-15,共2页
Chinese Journal of Microcirculation
