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严重左心室功能不全冠心病患者的外科治疗 被引量:7

Coronary Artery Bypass Grafting in Patients with Low Ejection Fraction
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摘要 目的总结有严重左心室功能不全[左心射血分数(LVEF)≤0.35]冠状动脉粥样硬化性心脏病(冠心病)患者行冠状动脉旁路移植术(CABG)的临床经验。方法18例有严重左心室功能不全的冠心病患者冠状动脉造影均显示为3支血管病变,在体外循环下行CABG,采用左乳内动脉18支与前降支吻合,采用桡动脉11支及大隐静脉26支与其它血管吻合。所有患者术前、术后均行正电子发射断层18F-脱氧葡萄糖显像(18F-FDGPET)检查,以判定心肌的存活状况。结果手术死亡1例,死于心室颤动。12例使用主动脉内球囊反搏(IABP),术后二次气管内插管3例。随访17例,随访时间14~26个月,所有患者心功能较术前均有不同程度的改善,LVEF(0.51±0.13)较术前(≤0.35)增大。2例出院后出现心绞痛复发。结论CABG是治疗严重左心室功能不全冠心病患者的有效治疗方法,其效果取决于存活心肌的多少及可再血管化的目标血管的数量。术中良好的心肌保护,积极应用IABP及护心通是手术成功的关键。
出处 《中国胸心血管外科临床杂志》 CAS 2005年第3期202-203,共2页 Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
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