摘要
首先分析了毛细管通道中流动的弯道效应及其产生的原因,接着在建立电渗流场数学模型的基础上,用有限差分法对弯道处内外壁面上不同电荷分布时的扩散进行了数值模拟· 根据计算结果,提出了一种基于改变弯道处内外壁面上电荷分布的新方法,以此使流场的弯道效应最弱· 同时还建立了分析和确定弯道处最佳电荷分布的优化方法· 结果表明。
The mechanism of dispersion induced by turn in the capillary electrophoresis channel flows was analyzed firstly. Then the mathematical model of electroosmotic flow is built, and the dispersion of the flow, with different distribution of charge at inner and outer wall in the turns, was simulated numerically using the finite differential method. A new approach of altering the distribution of charge at inner and outer wall in the turns was presented, based on the computational results, to minimize the dispersion induced by turn. Meanwhile, an optimization algorithm to analyze the numerical results and determine the optimal distribution of charge in the turns was also developed. It is found that the dispersion induced by turn in the capillary electrophoresis channel flows could be significantly suppressed by this approach.
出处
《应用数学和力学》
CSCD
北大核心
2005年第6期631-636,共6页
Applied Mathematics and Mechanics
基金
国家自然科学基金(重大)资助项目(20299030)
关键词
微流动
电泳
电渗
扩散
弯道
micro-flow
electrophoresis
electroosmotic
dispersion
turn
