摘要
以3-氯-4-三氟甲氧基苯胺为原料,经重氮化、甲醛肟化、水解和腈化反应得到纯度≥99.2%(GC)的3-氯-4-三氟甲氧基苯甲腈,总收率为31.5%。中间体及产物结构通过 IR 及元素分析验证。产物色泽好,腈化反应的溶剂可回收使用3次。
The 3-chloro-4-trifluoromethoxy benzonitrile was synthesized from 3-chloro-4-trifluorome- thoxy aniline by diazotization,formaldoximation,hydrolysis and cyanation.The overall yield was 31. 5% and the purity was ≥99.2%(GC).The structure of the intermediate and the product were con- firmed by IR and elementary analysis.The color of the product is excellent.The menstruum of cyana- tion could be recovered and reused for 3 times.
出处
《精细石油化工》
CAS
CSCD
北大核心
2005年第3期52-54,共3页
Speciality Petrochemicals
