摘要
目的 探讨氟脱氧葡萄糖 (FDG)正电子发射型体层摄影术 (PET)在非小细胞肺癌(NSCLC)三维适形放疗定位中的辅助作用。方法 13例非小细胞肺癌患者行FDGPET和CT检查 ,利用CT和FDGPET CT图像融合软件分别勾画大体肿瘤体积 (GTVCT和GTVPET CT) ,并对两者进行比较。结果 13例患者除 2例外 ,其他患者的GTVCT和GTVPET CT均不同 ,其中 5例GTVPET CT大于GTVCT,平均增加 2 9.2cm3 ;6例GTVPET CT小于GTVCT,平均减少 4 1.6cm3 。结论 与单纯CT图像相比 ,FDGPET CT融合图像不仅能更好地分清肿瘤与正常组织 ,而且对纵隔淋巴结具有更高的敏感性和特异性。。
Objective To study 18F-deoxyglucose-positron emission tomography and CT fusion (FDG PET) in three dimensional conformal radiotherapy for non-small -c ell lung carcinoma (NSCLC). Methods Gross tumor volume (GTV) of 13 NSCLC patient s were determined by FDG PET and CT separately (GTV PET-CT and GTV CT ), which were then compared. Results Except 2 patients, all the other patients' GTV PET-CT dif fered from their GTV CT. Compared with GTV CT, GTV PET-CT was in creased by an avera ge of 29.2?cm3 in 5 patients and decreased by an average of 41.6?cm3 in 6 patien ts. Conclusions 18F-deoxyglucose-positron emission tomography, which can improve target definition between benign and malignant lesions in the lung, is proved t o be more sensitive and specific in detecting mediastinal lymph node involvement . FDG PET may provide accurate target definition and improve the local control.
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
2005年第2期105-107,共3页
Chinese Journal of Radiation Oncology
