摘要
目的探索血清α—L—岩藻糖苷酶(AFU)活性测定在原发性肝癌(PHC)手术后疗效观察的临床意义。方法以比色法测定48例采用根治性手术治疗的PHC患者术前1周、术后3天、1周、2周、3周和2月的血清AFU值,与正常人(50例)血清AFU值进行比较研究。结果PHC患者术前、术后血清AFU值均高于正常对照组,差异有显著性(P<0.05);PHC患者术后3天血清AFU值开始明显下降,与术前相比有显著差异(P<0.05),3周达最低值,但是与1周和2周时比较无显著差异。结论血清AFU活性测定对于PHC疗效评估有较理想的应用价值。
Objective To explore the clinical significance of serum α-L-Fucosidase AFU activity detection in the curative effect survey of operated primary hepatic carcinoma PHC. Methods Technique of colorimetric was used to detect the serum AFU activity of normal controls 50 cases and the patients with primary hepatic carcinoma 48 cases in one week of pre-operation three days of post-operation one week of post-operation two week of post-operation and three week of post-operation. Comparison was performed among these groups. Results The serum AFU value was much higher in patients with PHC including pre-operation group and post-operation groups comparing with that in the normal controls. The differences were statistically significant P<0.05. The serum AFU value of three days of post-operation was declined obviously comparing that of one week of pre-operation group. The difference was significant as well. The serum AFU value of three weeks of post-operation was most low comparing that of one week and two weeks of pre-operation group. But the difference was not statistically significant. Conclusions Serum AFU activity detection should be considered as one of the ideal measurements in the evaluation of curative effect in PHC.
出处
《海南医学》
CAS
2005年第6期141-142,共2页
Hainan Medical Journal
关键词
血清AFU
PHC
比色法
serum AFU PHC technique of colorimetric
