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曲马多用于预防鼻内窥镜手术气管拔管期反应的临床观察

The Preventive Effect of Tramadol on Response of Patients to Extubation After Functional Endoscopic Sinus Surgery
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摘要 目的观察手术结束时静脉注射曲马多对预防鼻内窥镜手术患者气管拔管期反应的临床效果。方法60例ASAⅠ~Ⅱ级在全麻下行鼻内窥镜手术患者随机分为两组:预防组(A组)和对照组(B组),每组各30例。A组手术结束时静脉注射曲马多1mg/kg,B组手术结束时静脉注射0.9%氯化钠2ml。观察两组患者术后呼吸恢复时间、苏醒时间、拔管时间、镇静情况、拔管前后心率(HR)、血压(BP)、躁动发生率及不良反应。结果B组拔管时BP、HR明显高于A组(P<0.05),B组拔管后3min基本恢复到拔管前水平,A组各时间点的BP、HR比较平稳,A组拔管时躁动发生率低于B组(P<0.05)。结论手术结束时静脉注射曲马多能较好地预防、减轻鼻内窥镜手术患者气管拔管期反应。 Objective To observe the preventive effect of Tramadol on response of patients to extubation after functional endoscopic sinus surgery(FESS).Methods Sixty patients undergoing functional endoscopic sinus surgery were randomly divided into two groups:droperidol group A(n=30)and control group B(n=30).The patients in group A were intravescularly administered with 1 mg /kg Tramadol when operation was over,while the patients in group B were not. Wakening time,extubation time,agitation rate,sedation score of patiens were observed and the SBP,DBP and HR were also record respectively before extubation,at extubation,at 1 min and 3 mins after extubation.Results Blood pressure and HR rose markedly durring extubation and back to normal level 3 mins after extubation in group B while they were steady at all time points in group A.The incidences of agitation were lower in group A than those in controll group with a great significance. There was no significant difference of sedation score between group A and B.Conclusion Preventive administration of Tramadol can effectively prevent and reduce responses during the period of extubation in patients undergoing functional endoscopic sinus surgery.
出处 《江西医学院学报》 2005年第3期90-91,94,共3页 Acta Academiae Medicinae Jiangxi
关键词 曲马多 内窥镜手术 拔管期反应 气管 tramadol endoscopic operative,nose extubation reaction,trachea
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