摘要
目的探讨中西医结合对桥本甲状腺肿的临床疗效。方法收集我院2002年1月～2004年12月门诊桥本甲状腺肿病例共60例,男5例,女55例,年龄13～71岁,平均年龄(40.98±14.34)岁。其中25例单用优甲乐治疗作为对照组,35例以小剂量优甲乐加用中药治疗为观察组,通过观察治疗前后临床症状的改善及甲状腺球旦白抗体(TgAb)和甲状腺微粒体抗体(TmAb)的变化来观察其疗效。结果对照组临床症状完全缓解为0,显效1(4%),有效24(96%);观察组临床症状完全缓解为8(22.85%),显效14(40%),有效13(37.14%)。在临床症状疗效方面,观察组明显优于对照组(P<0.01)。TgAb治疗前后的变化:对照组显效8例,有效8例,无效9例;观察组显效8例,有效13例,无效15例。TmAb治疗前后的变化:对照组显效5例,有效8例,无效12例;观察组显效9例,有效8例,无效18例。两组比较无明显差异(P>0.05)。结论中西医结合治疗桥本甲状腺肿能明显改善临床症状,但对TgAb和TmAb的调节与单用西药组相比并无显著差异。
Objective To investigate the clinical efficacy of medicine and traditional medicine in the treatment of hypothyroidism caused by Hashimotos disease.Methods From January 2002 to December 2004,60 outpatients of hypothyroidism caused by Hashimotos disease were treated in Department of Endocrinology.Of 60 patients,5 were males,and 55 females.Their ages varied between 13 and 71 and average age was (40.98±14.3) years.Of these cases,25 cases treated only by thyroxine as controls,35 treated by thyroxine and traditional medicine as observations.The clinical efficacy was observed through looking into the amelioration of clinical symptom and the change of TgAb and TmAb before and after treatment.Results Clinical symptom of no case entirely disappeared,1(4%) obviously alleviated and 24(96%) alleviated in controls;8(22.85%) entirely disappeared,14(40%) obviously alleviated and 13(37.14%) alleviated in observations.The clinical efficacy of observations was much better than that of controls (P<0.01).For the change of TgAb after treatment,8 cases were obviously efficient,8 efficient and 9 inefficient in controls;8 cases were obviously efficient,13 efficient and 15 inefficient in observations.For the change of TmAb after treatment,5 cases were obviously efficient,8 efficient and 12 inefficient in controls;9 cases were obviously efficient,8 efficient and 18 inefficient in 34observations.There didn't exist obvious difference between controls and observations (P>0.05).Conclusion It can obviously improve clinical symptoms to use medicine and traditional medicine in the treatment of hypothyroidism caused by Hashimotos disease,but there wasn't obvious difference in the adjustment of TgAb and TmAb by comparison with controls.
出处
《中国临床保健杂志》
CAS
2005年第3期198-200,共3页
Chinese Journal of Clinical Healthcare
基金
北京中医药大学资助科研项目(Y2002-46)
关键词
甲状腺炎
自身免疫性
脾肾阳虚
中西医结合疗法
Thyroiditis,Autoimmune
Spleen-kidney yang defficiency
Zntegated chinese-western therapy
