摘要
目的:比较不同胰岛素给药方法对2型糖尿病治疗差异。方法:86例需胰岛素治疗的2型糖尿病患者住院进行了两种胰岛素强化治疗。(1)胰岛素泵连续皮下治疗组42例(CSII组);(2)多次皮下注射胰岛素治疗组44例(MSII组)。比较胰岛素泵治疗前后血糖变化、两组血糖达标时间、血糖达标时每日胰岛素的使用总量及低血糖的发生率。结果:2组患者最终均达到了目标血糖值,平均高血糖控制天数有显著性差异,CSII组:(7.84±4.13)d,MSII组:(10.26±3.26)d(P<0.01)。胰岛素用量CSII组:(37.57±7.86)u/d,MSII组:(40.26±6.25)u/d,无显著性差异(P>0.05)。而CSII组低血糖发生率低于MSII组,CSII组:(0.13±0.03)次/(人·d),MSII组:(0.24±0.06)次/(人·d),(P<0.01)。结论:CSII组可较MSII组更快更有效控制高血糖,并减少低血糖发生。
Objective To compare the effects of two different approaches of insulin delivery on hy- perghycemia. Methods Eighty-six type 2 diabetes were studied by 2 methods of intensive insulin deliv- ery, CSII group and MSII group. The average duration of treatment, insulin dosage and the hypo- glycemia were compared in the two groups. Results Both groups had reached the target BGs. The av- erage durations of treatment were significantly different, CSII(7.84±4.13) d, MSII(10.26±3.26) d (P<0.01). The insulin dosage was not significantly different, CSII(37.57±7.86) u/d, MSII(40.26 ±6.25) u/d (P>0.05).The hypoglycemia incidence in CSII was (0.13±0.03) times/(case·d), in MSII (0.24±0.06) times/(case·d) (P <0.01). Conclusion CSII can control the hyperglycemia much faster and more effectively, and reduce the hypoglycemia risk.
出处
《实用诊断与治疗杂志》
2005年第7期474-475,477,共3页
Journal of Practical Diagnosis and Therapy
