摘要
本文用Ki67单克隆抗体对11例乳腺浸润性导管癌、10例乳腺良性病变做了研究。结果显示乳癌Ki67标记阳性率较高(M 12.5),良性病变较低(M 8.15),两者间差异有显著性(P=0.05)。乳癌Ki67标记阳性率与核分裂计数和核面积呈显著正相关(相关系数分别为0.849,P<0.01和0.740,P<0.01)。未发现与淋巴结转移、肿物大小和年龄之间的相关性(P>0.05)。
Eleven cases of infiltrating duct carcinoma of breast and 10 cases of benign
breast lesions were studied by immuostain-ing with monoclonal antibody Ki67. The re- suits showed that Ki67 labeling rates of breast carcinoma were higher ( Median 12-5), benign lesions lower (Median 8- 15) , there was a significant difference between them (P = 0. 05). The Ki67 labeling rates of breast carcinoma were related to mitotic count and nuclear area (r=0. 849,P <0. 01; r=0. 740, P<0. 01 respectively).
There was not relation-ship between Ki67 labeling rates of breast carcinoma, lymph node involvement, tumor in diameter, and age (P>0. 05).
出处
《临床与实验病理学杂志》
CAS
CSCD
北大核心
1994年第4期293-295,T001,共4页
Chinese Journal of Clinical and Experimental Pathology
关键词
乳腺癌
KI67
免疫组织化学
抗体
乳腺疾病
breast lesions
breast carcino-ma
Ki67
immunohistochemistry
mitotic count
morphometry
