摘要
目的:观察帕米膦酸二钠(博宁)对多发性骨髓瘤骨痛的临床疗效。方法:1 6例多发性骨髓瘤患者静脉点滴博宁90mg,每2周～4周1次。结果:博宁治疗组对骨痛的总有效率为87. 5 %,强痛定对照组对骨痛的总效率仅为37. 5 %。博宁无明显不良反应。结论:博宁能有效缓解多发性骨髓瘤骨痛和活动功能障碍,并能协同化疗促进缓解、降低患者的高血钙水平。
OBJECTIVE:To observe clinical efficiency of pamidronate disodium (bolin) for the treatment of multiple myeloma (MM) with ostalgia. METHODS: 16 patients with MM were given bolin 90mg for intravenous injection, once every 2～4 weeks. RESULTS: The total effective rate of bolin treatment group for ostalgia was 87.5%, but AP-237 control group was 37.5%. Bolin had no obvious adverse reactions. CONCLUSION: Bolin can effectively relieve MM with ostalgia and functional disturbance, as well as coordinating chemotherapy to relieve and decrease high calcium level of the patients.
出处
《中国医院用药评价与分析》
2005年第3期168-169,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
多发性骨髓瘤
骨痛
膦酸类
治疗应用
multiple myeloma
ostalgia
phosphonic acid
treatment and application
