摘要
双氯芬酸钠与氯乙酸叔丁酯经酯化、水解反应制得非甾体抗炎药醋氯芬酸,收率82%。
Aceclofenac was synthesized in 82% overall yield from sodium diclofenac and t-butyl chloroacetate viaesterification and hydrolysis.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2005年第7期393-394,共2页
Chinese Journal of Pharmaceuticals
关键词
醋氯芬酸
非甾体抗炎药
合成
aceclofenac
non-steroid anti-inflammatory drug
synthesis
