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小儿下呼吸道感染的病原菌分析

Analysis of Pathogens of Lower Respiratory Tract Infection in Children
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摘要 目的了解小儿下呼吸道感染的病原菌种类及其药物敏感性,指导临床合理用药。方法对526例下呼吸道感染住院息儿做痰培养及药敏试验,并对痰培养阳性的132例进行病原菌及药敏分析。结果病原菌检出率25.1%。检出革兰阴性细菌85株(占64.4%),革兰阳性细菌47株(占35.6%)。其中大肠埃希菌(18.9%)、肺炎克雷伯菌(13.6%)、表皮葡萄球菌(9.8%)、铜绿假单胞菌(9.1%),溶血葡萄球菌(8.3%)为主要菌株。所有革兰阴性菌对亚胺培南敏感。结论大肠埃希菌、肺炎克雷伯菌为小儿下呼吸道感染的主要致病菌,亚胺培南、头孢吡肟对革兰阴性菌敏感。 Objective To investigate the pathogens causing lower respiratory tract infection and drug sensitivity of the pathogens, and direct the use of drugs for treating the infection. Method Sputum cultivation and drug sensitivity tests were performed for 526 children with lower respiratory tract infection. The pathogenic bacteria were identified and determined the drug sensitivity in 132 cases of positive reaction to sputum cultivation. Results The detectable rate of pathogenic bacteria was 25.1%, in which 85 strains of gram-negative bacteria (64.4%) and 47 strains of gram-positive bacteria(35.6%) were detected. Escherichiacoli(l8.9%) , Klebsiella pnenmoniae(13.6%), Staphylococcus epidermidis (9.8%), verdigris Pseudomonca (9.1%) and hemolytic Staphylococcus (8.3%) were the main strains. All of the gram-negative bacteria were sensitive to iraipenem. Conclusions Escherichia coli and Klebsiella pneumoniae became the main pathogenic bacteria of children's lower respiratory tract infection.The detected gram-negative bacteria were sensitive to imipenem and cefepime.
出处 《热带医学杂志》 CAS 2005年第4期536-537,共2页 Journal of Tropical Medicine
关键词 呼吸道感染 病原菌 耐药性 respiratory tract infection pathogenic bacteria drug tolerance
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