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唾液腺良性肿瘤患者唾液中CA125的表达及临床意义 被引量:5

Clinical implication on detection of CA125 in saliva from patients with benign tumors of salivary gland
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摘要 目的:探讨唾液腺良性肿瘤患者唾液中CA125的表达及其临床意义。方法:采集30例唾液腺良性肿瘤患者和30例健康对照者的唾液,采用酶联免疫吸附分析法(ELISA)检测唾液中CA125的含量,通过统计学软件进行比较分析。结果:唾液腺良性肿瘤患者唾液中CA125的含量为506.4±75.0U/L;显著高于健康对照者唾液中CA125的含量306.0±50.1U/L(P<0.05)。结论:唾液中CA125的检测对于判断唾液腺良性肿瘤具有一定的临床应用价值。 Objective:To investigate the expression and its clinical implication of CA125 in saliva from patients with benign tumor of salivary gland. Method:CA125 in saliva from 30 healthy persons and 30 preoperative patients who were confirmed with benign tumor of salivary gland by pathologic diagnosis were detected by the enzyme-linked immunoadsordent assay (ELISA). The results were analyzed SPSS 10.0.Result:The mean value of CA125 in saliva from healthy persons was 306.0±50.1 U/L. The mean value of CA125 in saliva from the patients with benign tumor of salivary gland was (506.4)±75.0 U/L, which was significant higher than that in healthy persons (P<0.05).Conclusion: The results suggest the potential clinical value of CA125 in saliva as a new tumor marker in benign tumor of salivary gland.
出处 《临床口腔医学杂志》 2005年第7期406-407,共2页 Journal of Clinical Stomatology
关键词 唾液腺 肿瘤 唾液 CA125 基因表达 口腔颌面部 salivary gland tumor saliva CA125
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