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脂联素在肾脏疾病中的意义 被引量：4

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摘要 脂联素(adiponectin)是脂肪细胞分泌的一种特异性蛋白质。研究发现脂联素与肥胖、2型糖尿病、胰岛素抵抗、动脉粥样硬化以及糖尿病的血管病变等都有一定的相关性,并证实了脂联素在这些疾病的发生发展中起着重要的作用;脂联素与肾脏病的关系也很密切,肾脏对脂联素的排泄和灭活有着重要作用,血浆脂联素浓度在各种肾脏病病人中均有变化,且与肾功能损害的严重程度密切相关。
作者 郭小芳 成兴波 卢国元
机构地区 [
出处 《国外医学（泌尿系统分册）》 2005年第4期543-546,共4页 Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
关键词 肾疾病 蛋白质类
分类号 R692 [医药卫生—泌尿科学]
  • 相关文献

参考文献19

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二级参考文献38

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共引文献15

同被引文献46

  • 1杨成悌,李小平.脂联素的研究进展[J].医学综述,2004,10(7):403-405. 被引量：10
  • 2黄宇虹,高秀梅,张伯礼.脂联素的研究进展[J].中国临床药理学与治疗学,2004,9(9):961-965. 被引量：17
  • 3李春霖,龚燕平,田慧,陆菊明,李明,肖或君,母义明,潘长玉.脂联素受体在正常Wistar大鼠各组织的分布和表达[J].解放军医学杂志,2005,30(8):718-719. 被引量：23
  • 4季大玺 谢红浪.血液透析[A].林善锬.当代肾脏病学[C].上海:上海科技教育出版社,2001.824-835.
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  • 6Kharroubi I,Rasschaert J,Decio L,et al.Expression of adiponectin receptors in pancreatic Bcells.Biochern Biophys Res Commum,2003,312(4):1118-1122.
  • 7Fasshauer M,Klein J,Kralisch S,et al.Growth homoneisa positive reguhto of adiponectin receptor 2 in 33"3-LI adipocytes.F FBS Lett,2004,558(123):27232.
  • 8Yarnauchi T,Kamon J,Waki H,et al.The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.Nat Med,2001,7(8):941-946.
  • 9lwaki M,Matsuda M,Maeda N,et al.Induction of adiponectin,aft-derived antidiabetic and antiatberogenie factor,by nudear receptors.Diabetes,2003,52(7):1655-1663.
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引证文献4

二级引证文献11

国外医学（泌尿系统分册）
2005年 第4期

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