摘要
目的对微量元素在癌组织中的含量进行研究分析,探讨这些元素,在肿瘤发生发展及诊断中的意义。方法收集68例胃癌患者癌组织及癌旁组织(对照组),用原子吸收分光光度法和荧光光度法测定Se、Zn、Cu、Fe、Cd。结果癌组织Se低于癌旁组织,Cu高于癌旁组织差异有显著性(P<0·01和P<0·05);Zn在癌组织内的含量低于癌旁组织,Fe、Cd在癌组织内的含量高于癌旁组织,但差异均无显著性。结论Se、Zn、降低和Cu、Fe升高,可能与癌发生相关,对诊断和鉴别癌症有一定意义。
Objective To study the significance of trace elements in the development and diagnosis of cancer through analyzing the contents of trace elements in the cancer tissues. [Methods] Cancer tissues of 68 carcinoma ventriculi patients and side tissues of the control group were collected; Se、Zn、Cu、Fe、Cd were determined with atomic absorption spectrophotometry and fluorophotometry. [Results] The contents of Se and Zn in the carcinoma tissues were lower than that in the carcinoma side; the contents of Cu, Fe and Cd in the carcinoma tissues were higher than that in the carcinoma side (P<0.01, P<0.05). The difference was not significant. [Conclusion]The decrease of Se and Zn and the increase of Cu and Fe might be related with the attack of cancer, which is significant for the diagnosis.
出处
《职业与健康》
CAS
2005年第8期1167-1168,共2页
Occupation and Health
关键词
胃癌
癌旁组织
微量元素
Carcinoma ventriculi, Carcinoma sides, Trace elements
