摘要
【目的】评价高压氧(hyperbaricoxygen,HBO)治疗脑动脉硬化症的疗效。【方法】400例脑动脉硬化症患者随机分为HBO治疗组200例,对照组200例。通过对两组的症状、体征、血液流变学、治疗前后的改变进行疗效评价,并根据HBO治疗前后脑动脉脉动指数,脑动脉血流的改善,并对HBO治疗脑动脉硬化症的作用机制进行了探讨。【结果】HBO组患者眩晕、头痛、失眠、记忆力、计算力、精神状态等的改善较对照组疗效明显(P<0.005),治疗组血液流变学指标提示全血粘度及血浆粘度均明显降低(P<0.01),TCD见HBO治疗后大脑前、中动脉的脉动指数明显下降(P<0.05,P<0.01);而对照组血液流变学、TCD改善均不明显。【结论】HBO治疗脑动脉硬化疗效确切、可靠,优于单纯药物治疗。
[Objective]To evaluate the effects of hyperbaric oxygen (HBO) therapy on patients with cerebral arteriosclerosis.[Methods]Seven Hundred cases of cerebral arteriosclerosis were randomly divided into treamtent group (n=350 , receiving hyperbaric oxygen therapy plus routine treatment) and control group (n=350, only receiving routine treatment) . The examinations of TCD and blood rheology at differen periods were performed.[Results]In the treatment group , the recovery rate and effective rate were significantly higher than in the control group (P<0. 01). In the treatement group , the parameters (whole blood viscosity and plasma viscosity) for blood rheology were obviously decreased(P<0.01). TCD revealed that the cerebral ischemic loci were improved in varying degrees.[Conclusion]Hyperbaric oxygen plus routine treatment can effectively treat cerebral arteriosclerosis .
出处
《医学临床研究》
CAS
2005年第7期903-905,共3页
Journal of Clinical Research
关键词
脑动脉硬化/治疗
高压氧
cerebral arteriosclerosis/TH
hyperbaric oxygenation
