摘要
本文用紫外分光光度法对硫酸长春新碱在0.9%氯化钠注射液中的稳定性,按经典恒温加速试验法进行了动力学实验研究,结果表明,硫酸长春新碱的降解为一级反应。25℃,32℃时硫酸长春新碱的有效期t0.9分别为12.51h,8.86h。为临床合理用药提供了确切的数据。
UV-spectrophotometry was used for the study on the stability of vincristine sulfate
in0.9%sodium chloride injections bythe classical censtant temperature accelerative kinetic test.
The result showed that the degradation of vincristine sulfate was thefirst-order reaction. At 25, 30
℃the t0.9 of Vincristine sulfate were 12. 51h and 8.86h respectively,data for the rational useof the
medicine for patient were suggested.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1995年第4期165-167,共3页
Chinese Journal of Hospital Pharmacy