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蛙皮素及其同类物与肿瘤的关系 被引量:4

Relationship between Bombesin and Its Analogues and Carcinomas
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摘要 1971年Anastasi等从一种欧洲雨蛙的皮肤中分离出蛙皮素(BN),此后,又有学者在人及哺乳动物体内发现了蛙皮素的同类物:胃泌素释放肽(GRP)和神经调节肽B(NMB),并发现蛙皮素及其同类物可通过相应受体刺激多种肿瘤的生长。从此,人们对其进行了广泛的研究。现就近年来关于BN及其同类物与肿瘤生长关系的研究作一综述。 Anastasi detached bombesin from the skin of a kind of European frog in 1971.After that,other researchers discovered its analogues in the body of human and mammals:gastrin-releasing peptide and neuropeptide B.They also found that bombesin and its analogues could stimulate the growth of many kinds of tumors through their respective receptors.Hence,they were studied widely.The research progresses in the relationship between bombesin or its analogues and carcinomas are reviewed.
作者 王东旺
机构地区 江西省人民医院
出处 《现代诊断与治疗》 CAS 2005年第4期225-227,共3页 Modern Diagnosis and Treatment
关键词 蛙皮素 胃泌素释放肽 神经调节肽B 肿瘤 Bombesin Gastrin-releasing peptide Neuropeptide B Carcinoma
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  • 1Anastasi A, Erspamer V, Bucci M,et al. Isolation and structure of bombesin and alytesin, two analogous active peptides from the skin of the European amphibians bombina and alytes [J]. Experientia, 1971,27(2): 166-167.
  • 2Preston SR, Woodhouse LF, Gokhale J, et al. Characterization of a bombesin/gastrin-releasing peptide receptor on a human gastriccancer cell line[J]. Intern J Cancer, 1994,57(5):734-741.
  • 3Falconieri EG, Severini C, Erspamcr V, et al. Parallel bioassay of 27 bombesin-like peptides on 9 smooth muscle preparations structure-activity relationships and bombesin receptor subtypes [J]. Regul Pept, 1988,21(1-2):1-11.
  • 4McDonald TJ,Jomvall H, Nilsson G, et al. Characterization of a gastrinreleasing peptide from porcine non-antral gastric tissue[J]. Bioehem Biophys Res Commun, 1979,90(1):227-233.
  • 5Minarnino N, Kangawa K, Matsuo H, et al. Neuromedin C:a bombesin-like peptide identified in porcine spinal cord [J]. Biochem Biophys Res Commun, 1984,119(1):14-20.
  • 6Minamino N, Kangawa K, Matsuo H, et al. Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord [J]. Biochem Biophys Res Commun ,1983,114(2):541-548.
  • 7Spindel ER,Gibson BW,Reeve JR Jr,et al. Cloning of cDNAs encoding amphibian bembesin: evidence for the relationship between bembesin and gastrin-releasing peptide[J]. Proc NASUA,1990,87(24);9813-9817.
  • 8Spindel ER. Mammalian bombesin-like peptides [J]. Trends Neurosci,1986,9:130-133.
  • 9Hoist J J, Harling H, Messdl T, et al. Identification of the neurotransmitterl neuromodulator functions of the neuropeptide gastrin-releasing peptide in the porcine antrum, using the antagonist (Leul3-psi-CH2NH-Leul4)-bombesin[J]. Scand J Gastroenterol, 1990,25(1):89-96.
  • 10Miyata M, Rayford PL,Thompson JC, et al. Hormonal (gastrin, secretin,cholecystokinin) and secretory effects of bombesin and duodenal acidification in dogs[J]. Surgery, 1980,87(2):209-215.

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