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几种常用方法治疗Graves病的预后探讨 被引量:7

PROGNOSIS OF GRAVES DISEASE TREATED WITH DIFERENT MODALITIES OF THERAPY
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摘要 回顾性地观察了224例Graves病于停止治疗6个月至10年以上的预后,分三组,采用(1)长期抗甲状腺药物的82例;(2)放射性碘治疗的100例;(3)甲状腺次全切除的42例。根据临床表现和实验室检查从治愈率、复发率、甲状腺功能低减的发生率来评价预后。长期抗甲状腺药的治愈率较一般报道的高,10年时可达75%。三组治疗中放射性碘疗效最高,甲状腺手术组发生永久性甲状腺功能低减者较低,甲状腺机能亢进伴突眼者有97.3%于三种方法治疗后获得改善。 retrospective study on the prognosis ofGraves disease was carried out.224 cases,whose treatment has been stopled for 6 months to more than 10 years,were divided into 3 groups. 82 cases received long-term antithyroid drug therapy,100 cases were treated with radioactive ̄[3] I and 42 cases had subtotal thy-roidectomy.The prognosis was evaluated for 4 items according to clinical and laboratory investigations.The cured rate of long-term drug therapy in this study was higher than that reported by most of other authors, ̄[3]I therapy was the best among the 3 mOdalites of therapy,The incidence of permamant hy-pothyroidism was fairly low in the thyroidectomy group.97.3%of the patients with exophthalmos showed improvement after treatment in all the 3 groups.
机构地区 北京协和医院
出处 《中华内科杂志》 CAS CSCD 北大核心 1995年第1期38-41,共4页 Chinese Journal of Internal Medicine
关键词 预后 突眼性甲状腺肿 放射疗法 甲状腺切除 Prognosis Graves,disease Thyroid antagonists Radiotherapy Thyroidec-tnmy
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  • 1朱禧星,实用内科学.下,1986年
  • 2徐竟英,中华核医学杂志,1982年,2卷,193页

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