摘要
应用光镜和显微图像分析软件，对１７例乳腺良性病变及４６例乳腺癌针吸细胞学标本核仁组成区相关蛋白（Ａｇ－ＮＯＲｓ）进行了检测。结果表明，与乳腺良性病变比较，乳腺癌细胞核内Ａｇ＋ＮＯＲｓ数目显著增多，每个Ａｇ＋ＮＯＲｓ占有平均面积百分比显著减少。乳腺癌转移组与无转移组癌细胞核内ＡｇＮＯＲｓ数目虽无显著差异，但每个Ａｇ－ＮＯＲｓ占有平均面积的百分比差异显著，提示Ａｇ－ＮＯＲｓ检测有助于乳腺良恶性肿瘤的鉴别，且对乳腺癌预后的评估有一定参考意义。
AbstractThe argyrophilic nucleolar organizer regions(Ag-NORs ) was measured in the tissue sample aspiratedwith fine needle for 17 cases of breast benign lesion and46 cases of breast cancer ,by analysis of their micro-image with light microscope and computed.The resultsindicated that the amount of Ag-NORs in the nuclei ofbreast cancer was increased while the percentage of av-erage areas occupied by Ag-NORs was decreased.Itwas significant statistically in comparing with benignlesion(P< 0,05 ).In addition,the amount of AgNORs in the nuclei of breast cancer with and that with-out metastasis was not different markemv(P>0.05)。However the percentage of average areas occupied byAg-NORs was different statistically(P< 0.05 ).Theconclusion of Ag-NORs is of benefit to distinguish frombenign and malignant tumours of breast as well assignificant for evaluating the prognosis for breast can-cer。
出处
《中华外科杂志》
CAS
CSCD
北大核心
1995年第10期609-610,共2页
Chinese Journal of Surgery
