摘要
于1992年12月~1993年2月在胃癌高、中、低发区以家庭为为单位进行幽门螺杆菌感染的血清流行病学调查。结果:在胃癌高、中、低发区HP阳性率分别为59.4%、55.9%33.5%;平均抗体水平为2.30+0.49、2.04±0.47、1.84±0.46(-χ±s)。高发区的感染率及抗体水平均明显高于低发区(Ρ<0.05、Ρ<0.01),且感染的年龄早。HP感染率与胃癌死亡率的高低呈平行趋势。说明HP感染可能与胃癌有关。
From December 1992 through
February 1993, we have investigated the prevalence ofHelicobacter pylori(HP) infection in
areas of high,middle and low incidence of gastriccancer. The results showed positive rates of
HP infection were 59.4%、55.9%and 34.5%, andmean level of HP IgG antibody were 2.30±
0.49,2.04±0.47 and 1.48±46 respectively,in areasof high,middle and low incidence of gastric
cancer. The infective rate and the mean level ofIgG in the high incidence area were obviously
higher than that of low incidence area,especially amoung young people. The HP infective rate
was positively related to the mortalityof gastric cancer. These results indicate that HP infection
may play a causal role in thepathogenesis of gastric caner.
出处
《中华消化杂志》
CAS
CSCD
北大核心
1995年第5期276-278,共3页
Chinese Journal of Digestion
关键词
胃癌
幽门螺杆菌
流行病学
Gastric
cancer
Helicobacter pylori
Seroepidemiology.