摘要
报告３０例ｔ（８；２１）急性髓细胞白血病（ＡＭＬ），２６例为Ｍ＿（２ｂ），４例为Ｍ＿（２ａ）。初始完全缓解率为０．９６２。０．７６２的男性患者伴有－Ｙ，０．２２２的女性患者伴有－Ｘ，０．２６７的患者伴有其它染色体异常。免疫表型分析ＨＬＡ－ＤＲ／ＤＰ阳性率０．１００，ＣＤ＿（３８）为０．８６６，ＣＤ＿（１５）为０．５００，ＨＩＭ＿４、ＨＩＭ＿５均为０．８００。ｔ（８；２１）ＡＭＬ与ＡＭＬＭ＿（２ｂ）的关系需进一步深入研究。
hirty patients with t( 8;21) acute myeloid leukemia( AML) were analyzed.Their morphological diagnosiswere M_(2b) in 26 and M_(2a) in 4 cases,respectively.Thecomplete remission rate after initial induction chemother-apy was 9 6.2%. Sex chromosome loss was found in76.2%of male and 22.2%of female patients. In26.7%of the cases there were other additional chromo-some abnormalities.For immunophenotypes,HLA-DR/DP was positive in 1 00%,CD_(38) in 86.5%, CD_(15) in 50. 5%,and HIM_4 and HIM_5 both in 80.0% patients. Therelationship between t ( 8;21) AML and AML M_(2b) isworth further researching.
出处
《中华血液学杂志》
CAS
CSCD
北大核心
1995年第4期190-192,共3页
Chinese Journal of Hematology
关键词
白血病
髓细胞性白血病
染色体异常
免疫表型
Leukemia,myeloid, acute AML-M_(2b) t( 8
21)(q22
q22)Im-munophenotype
