摘要
采用大鼠TBSA15%Ⅲ度烧伤模型,伤后创面涂绿脓杆菌后共分6组。其中5个组的创面分别涂以不同药物,对照组不涂药。通过对各组创面外观、痂下细菌定量与病理组织学观察,皆证实AgSD-ZnSD-A霜组效果最好,是满意的烧伤外用药。
48 Wistar rats were scalded resulting in 15% TBSA full-thickness burn. Pseudomonas aeruginosa(10~9/ml)was inoculated to the wounds.The rats were divided into 6 groups.5 different topical agents were separately applied to the wounds constitut- ing 5 groups,and no drug was used in control group.Through observing the appearance of wound,the quantity of bacteria in the subeschar tissue and histo-pathological changes,we confirmed that AgSD—ZnSD—A cream was a satisfactory topical agent.