摘要
对１１６例酒精性肝病（ＡＬＤ）肝穿标本进行了病理观察。其中具肝细胞脂变者９９例，占８５％。依脂变程度将其分为Ⅰ～Ⅳ级，脂变肝细胞≥３０％诊断为酒精性脂肪肝（ＡＦＬ）。Ⅰ级：脂变肝细胞＜小叶３０％；Ⅱ级：＞３０％（轻度ＡＦＬ，１９例）；Ⅲ级：＞５０％（中度ＡＦＬ，６例）；Ⅳ级：≥７０％（重度ＡＦＬ，２例）。对酒精性肝脂变的特点进行了观察：轻者呈散在或小灶状大泡状脂变，主要分布于小叶的Ⅱ区和Ⅲ区，严重者脂变甚弥漫，脂变处网状支架多完整保存，常同时伴有ＡＬＤ其它一些基本病变，如窦周纤维化、小坏死灶及小型肝细胞等。以上病理特点有利于从病理上与其它原因所致肝脂变进行鉴别。
Among 116 liver biopsy specimens of alcoholic liver
disease(ALD), 99 showed fatty degeneration in which 27 cases were
diagnosed as alcoholic fatty liver(AFL)that the number of fatty
liver cells >30%.FL was divided into three grades,i.e.mild AFL (fatty
liver cells >30%)19 cases ,moderate AFL(>50%) 6 cases and severe
AFL(>75%) 2 cases.The characteristics of alcoholic liver fatty
degeneration were as follow:mild one showed that the liver cells
contaied fatty large-droplet were mainly distributed in 2 and 3 zone
of lobes in scattered and focal form; severe one expressed that fatty
liver cells were diffusely distributed. Reticulum stand was intactly
reserved. AFL often accompanied with some other basic changes of ALD,
such as perisinusoidal fibrosis ,small focal necrosis with neutrophil
infiltrition and small liver cells.
出处
《中日友好医院学报》
1995年第1期30-32,共3页
Journal of China-Japan Friendship Hospital
基金
中日友好医院科研基金
关键词
酒精性肝病
肝细胞脂变
脂肪肝
病理
alcoholic liver
disease
liver cell fatty degeneration
alcoholic fatty liver
