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散发性重型戊型病毒性肝炎11例的临床、病原学、病理特征 被引量:2

Clinical, Etiological and Pathological Feature of 11 Patients with Sporadic Fulminant Hepatitis E
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摘要 本组病例有63.6%的患者病前喜食水生贝类及生冷食物,经常在餐馆就餐,有可能经食物源传播;27.1%病例发病前1~2月在境外生活,可能有输入性传播,54.5%是在慢性HBV感染基础上重叠感染HEV,与印度报道相一致,提示这是HBV高发区HEV感染的一个特点。本组FH—E的临床特点为黄疸深、退黄时间长,肝功能损害明显,并发症以肝性脑病及继发感染为多见.病理组织学特征是汇管区有明显炎性细胞浸润及毛细胆管扩张、增生。 The results showed that the sporadic fulminant hepatitis E (FH-E) was different from epidemic FH-E. The features of sporadic FH-E are that:1) The male was more than the female (9 men, 2 nonpregnant women). 2)The elderly person was more susceptive. The mean age was 49. 2±11. 5 years, in which, 63. 6% of patients with sporadic FH-E were aged over 50 years. 3) 7/11 (63. 6%) of patients liked to eat rare shell-fish, before illness and 3/11 (27. 3%) of patients had returned from Taiwan, Hangkong or oversea. 4) 6/11 (54.5%) of patients with sporadic FH-E had HEV and HBV superinfection. 5) The patients with sporadic FH-E had serious complication and high mortality (6/11, 54. 5%).
机构地区 深圳市东湖医院
出处 《中西医结合肝病杂志》 CAS 1995年第2期9-11,共3页 Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
关键词 重型肝炎 戊型肝炎 散发性 病理 病原学 Fulminant Hepatitis Type E Sporadic Cases HEV and HBV Superinfection
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