摘要
采用热板法测痛，预先给予小鼠对氯苯丙氨酸对３，１５－二乙酰苯甲酰乌头宁的镇痛作用无明显影响；损毁大鼠的中缝大核，对３，１５－二乙酰苯甲酰乌头宁的镇痛作用亦无明显影响，结果提示３，１５－二乙酰苯甲酰乌头宁的镇痛作用可能与中枢５－羟色胺能系统无明显关系。
n the hot plate test,it was shown that
3,15-diacetylbenzoylaconine(DABA)-inducedanalgesia was not influenced
significantly by pretreatment of p-chlorophenylalanine in miceand no
notable influence was seen on the analgesia effect of DABA after
lesion of the rat mu-cleus raphe magnus(NRM).It is suggested that the
analgesia effect mediated by DABA maynot be remarkably related to the
central serotoninergic system.
出处
《包头医学院学报》
CAS
1995年第4期4-6,共3页
Journal of Baotou Medical College
基金
国家自然科学基金
关键词
二乙酰苯甲酰
乌头宁
对氯苯丙氨酸
镇痛
药理学
diacetylbenzoylaconine
analgesia
p-chlorophenylalanine
nucleusraphe
magnus
