摘要
本文报道了血浆及部分组织中精氨酸加压素免疫活性物质(ir-AVP)在大鼠烫伤休克时的动态变化。放射免疫测定的结果表明,大鼠烫伤休克后即刻、60、120、180和240min,血浆ir-AVP含量均显著升高;而垂体后叶ir-AVP含量则显著降低。提示烫伤休克时,垂体后叶向循环中释放加压素的量增加。另外烫伤休克时,下丘脑、垂体前叶、桥延脑、脊髓及肾上腺等组织中的ir-AVP含量也有不同程度的变化,其意义如何有待进一步探讨。
The dynamic changes of immunoreactivr argininc vasoprrssin (Jr-AVP) contents in the plasma and some tissues in burned rats were observed in this study.Radioimmuno-assay showed that the ir-AVP contents in tho plasma were significantly increased immediately,, 60, 120, 240 min after burn while in the posterior pituitary the ir-AVP content was significantly decreased, suggesting the release of AVP from the posterior pituitary into the plasma in burn shock.The ir-AVP contents in.the hypothalamus, anterior pituitary, pons-medulla oblongata, spinal cord and adrenal gland also displayed changes to different extent under burn shock condition, the significance of which needs further study.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
1989年第4期33-33,共1页
Academic Journal of Second Military Medical University
关键词
精氨酸加压素
烫伤
休克
动物
arginine vasopr-rssin
burn
shock- radioimmunoassay
disease models,animal
