摘要
分析了在某医院收集到的４５株阴沟肠杆菌对１２种常用抗生素的耐药情况。院内外菌株都耐氨苄青霉素，院内菌株有６０％以上对羟苄青霉素、复方新诺明、氯霉素、头孢哌酮、头孢噻肟、头孢他啶等６种抗生素产生耐药性，而院外菌株对这些抗生素有较高的敏感性，院内菌株具有高耐药率和多重耐药的特点。目前，对阴沟肠杆菌比较敏感的药物有：丁胺卡那霉素、氟哌酸、吡哌酸。院内菌株对丁胺卡那霉素、氟哌酸和吡哌酸的耐药率分别只有７．７％、１７．９％和２５．６％。
usceptibility
of 45 clinical isolates of Enterobacter cloacae(E. cloacae)to 12
common antibiotics wasanalysized. both community and nosocomial E.
cloacae was resistant to ampicillin. More than 60%ofnosocomial E.
cloacae was resistant to carbenicillin、trmeth-sulfa、
chloramphenicol、 cefoperazone、cefo- taxime and ceftazidime 6
antibiotics,whereas community E. cloacae was relatively sensitive to
these antibi- otics. 84.6% of nosocomial E. cloacae was resistant to
more than 7 antibiotics,but community E. cloacaewas resistant to less
than 6 antibiotics. Nosocomial E. cloacae had the feature of
possessing high resistantrate and multiresistance. Nowdays the
antibiotics to which the E. cloacae was sensitive were amikacin,
norfloxacin and pipemidic acid.The resistant rate of E. cloacae to
amikacin, norfloxacin and pipemidic acidwere 7.7%,17.9% and 25.6%
respectively.
出处
《第一军医大学学报》
CSCD
1995年第3期213-214,共2页
Journal of First Military Medical University
关键词
阴沟肠杆菌
医院感染
抗生素
耐药性
Enterobacter cloacae
nosocomial
infection
resistant rate
